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Frontiers in Physiology

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Glutathione (GSH) reduces disulfide bonds in cytoplasmic proteins to cysteines, in which it is converted to its oxidized form GSSG

284 Dysregulated MT expression in ascending aortic smooth muscle cells from patients with bicuspid aortic valve (BAV) might lead to an insufficient response to oxidative stress, potentially triggering aneurysm formation

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(PubMed) Montgomery SA, Thal LJ, Amrein R