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Oberlick EM, et al

There are a number of things that could be going on and explain the deterioriation in mood - some people don't respond well to methyl - some people need much higher levels of B12 post loading shots - potentially much higher than the normal or even measurable range

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Additionally, this study was designed to investigate safety and tolerability, thus secondary weight management outcomes must be interpreted in context

The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts

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