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Also, LBM reduction was often assessed using BIA or DXA, both of which have limitations in distinguishing between muscle, organ mass, and extracellular fluid

doi:10.1111/andr.12236

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Abstract The development of tirzepatide, a first in class dual glucose dependent insulinotropic polypeptide and glucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management of type 2 diabetes and obesity