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IGF-1 stimulates activation of ER, which consequently binds to IGF-1R, inducing downstream phosphorylation of AKT and ERK1/2 leading to increased cell growth via enhanced IGF-1-signaling pathways [109]

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However, both should be prescribed and monitored by a licensed physician, as combining peptide therapy with other metabolic interventions increases the complexity of dosing and side effect management

L-Carnitine supplementation reduces the general fatigue of cancer patients during chemotherapy

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