Extrinsic aging is predominantly influenced by sun exposure (photoaging), although smoking and pollution also play a role.1 Intrinsic and extrinsic aging overlap in clinical practice.1 Demand for strategies to mitigate the signs of skin aging is high.2 Recent studies suggest that regular exercise, apart from improving quality of life and reducing the risk of mortality and chronic disease,2 might also reduce the thickness of the stratum corneum and improve dermal thickness and collagen content.3 Diet is also important, with a number of studies highlighting its role in the prevention of aging
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Medication data included semaglutide dosing categorized as low dose (0.25 to 1 mg weekly) and high dose (1.7 to 2.4 mg weekly), and dose and type of systemic HRT (transdermal or oral estrogen and progestogen use)
DPP4 serum levels of morbidly obese men are elevated compared with lean controls and significantly correlated with BMI, the size of adipocytes in subcutaneous and visceral fat, and the adipocyte hormones adiponectin (negatively) and leptin
Improved exercise performance: Better fat utilization can help spare glycogen stores, allowing athletes to maintain performance for longer before fatigue appears
A person who eats less because the drug removes hunger, but doesn't change the structure or composition of what they eat, builds nothing transferable
