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48 Although NT4/ knockout mice do not show impaired neurogenesis, 45 this might be attributed to compensatory mechanisms that could develop because such transgenic mice do not express NT4 from as early as their embryonic development

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This includes large countries such as India, Canada, China, Brazil and Turkey which make up 40% of the worlds population and an estimated 33% of the worlds population of adults living with obesity [13]

When P-15 is added in scaffold material, it results in a significantly higher gene expression of alkaline phosphatase (ALP), BMP-2 and BMP-7 [235]

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