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In mice pretreated with buthionine sulfoxime to inhibit GSH synthesis and induce a deficient state, oral administration of GSH resulted in statistically significant increases in GSH concentrations in kidney, heart, lung, brain, small intestine, and skin, but not in the liver

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There is absolute chance of presence of undesirable particles or endotoxins in solution, so sterile filter is used in pharmaceutical industry to get rid of all of them

[] however, it does not have any effect on other essential metals like iron, zinc, magnesium and calcium

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