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Financial Impacts at Federal and State Levels Federal Level Increased Spending: Medicare spending on GLP-1 medications could rise by $24$37 billion over the next several years, depending on the breadth of the coverage expansion and member uptake rates

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Higher concentrations (e.g., 5mg/mL using 1mL bacteriostatic water) reduce injection volume but increase the risk of dosing errors if syringes lack sufficient precision

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When You Should See a Specialist Or Stop Treatment If a clinician suspects a true allergic reaction, they may recommend stopping tirzepatide and referring to an allergist for testing, or initiating short-course corticosteroids or other targeted treatments

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