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Leukaemia: a model metastatic disease

Final approval of the version to be published (all authors), and agreement to be accountable for all aspects of the work (all authors)

Biochim Biophys Acta Bioenerget

Preclinical studies have compellingly demonstrated the efficacy of various strategies, including microglial modulation, neurotrophic factor regulation, and NMDA receptor antagonism, in alleviating tinnitus-like behaviors in animal models

Shown to repair tendon and ligament injuries in clinical models

Nonetheless, the administration of metformin hampers the functionality of the electron transport chain within mitochondrial respiratory complexes, resulting in diminished adenosine triphosphate (ATP) synthesis