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Patients were classified as severe asthma defined by 2014 European Respiratory Society/ATS guidelines (41)

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Documented effects in published research include collagen and elastin synthesis stimulation, fibroblast activity modulation, gene expression changes related to anti-inflammation and tissue repair, antioxidant pathway activation, and effects on hair follicle stem cells

doi: 10.1016/j.ccr.2010.08.009

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