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Additionally, as the first CVD to develop in patients with diabetes is often heart failure rather than myocardial infarction [1], it is becoming clear that the pathology of diabetes itself causes heart failure through direct effects on cardiomyocytes and other myocardial cell types

This interaction site is less defined but comprises the glutathione moiety of Grx(SSG), parts of helix 3, and a conserved lysine/arginine residue that also contributes to the scaffold site 14,15

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Preparation of CBD also affects its bioavailability

doi: 10.3390/nu15153375 Pascolini D, Mariotti SP