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Hackshaw says that he has patients complete a fibromyalgia impact questionnaire at each visit

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This naturally distributes injection points across the available tissue area without requiring complex tracking systems

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This suggests low surface exposure or minimal contribution, which may indicate either highly exposed tyrosine in a hydrophilic environment (Aderinola et al., 2020) or enhanced energy transfer from tyrosine to tryptophan due to strong proteinprotein interactions (Malomo & Aluko, 2015)