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The applicant also noted that only the aprevo insertion instrumentation, cleared by FDA, is authorized to implant the aprevo Cervical interbody device, and these instruments are not available to be purchased separately for use with other devices

Innes JF, Fuller CJ, Grover ER, Kelly AL, Burn JF

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Veronin MA, Schumaker RP, Dixit R

Some mechanistic evidence suggests these may actually be anti-anabolic by suppressing mTOR pathways involved in muscle protein synthesis

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