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Doctors aren't sure what causes the virus to reactivate in people who have periodic outbreaks, but they think the following may increase your risk of having one: Being out in the sun for a long time or when the sun is very bright or intense Having a fever or an illness Emotional stress Having your period if you're assigned female at birth (AFAB) Physical stress, such as an injury or having surgery You're more likely to have a recurrent infection the first year after you're infected

These active forms are crucial cofactors for enzymes involved in DNA synthesis, fatty acid metabolism, and amino acid metabolism

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But, lately, it feels like one of the big macro trends in the space has companies packaging up things that our bodies already produce and marketing them back to us

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Ferroptotic macrophages can trigger a systemic inflammatory response by releasing DAMPs and pro-inflammatory cytokines that can activate the inflammasome