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A study found that individuals with androgenetic alopecia exhibited higher levels of oxidative stress markers in their scalps compared to those without hair loss

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Oxidative stress happens through several ways: Homocysteine goes through oxidation and auto-oxidation [18] Low folate reduces antioxidant enzyme activities, including superoxide dismutase and glutathione peroxidase [18] These changes create an environment that hurts cell function [18] Folate supplements can work as antioxidants by lowering homocysteine levels and boosting intraerythrocyte glutathione directly [19]

It may eventually involve physical processes, such as polymer recrystallization, or denaturation of protein structures