Vitamin B12 injections are medically necessary when a patient has severe deficiency, neurological symptoms requiring rapid correction, or a condition that prevents adequate oral absorption
The safety profile is comparable across injection, oral, and sublingual forms
Sean Daneshmand looks at the overall picture, fully envisioning the likely outcome of each treatment in order to choose the one with the highest possibility of achieving the desired goal
These individuals may need much higher doses or may not see the same results as they would with injections
While both Vitamin B12 injections and oral supplements have their place, the decision ultimately comes down to your unique health needs
It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile