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Its launch, however, marks a meaningful step forward in expanding care for Medicare beneficiaries

Although these drugs have been used to treat type 2 diabetes for nearly two decades, it was not until 2021 that the US FDA approved them for treating obesity

Planning for long-term use, including financial considerations, sets realistic expectations

A 2025 mechanistic review published in The Journal of Clinical Endocrinology and Metabolism showed that tirzepatide, which activates the GIP receptor, showed less BMD loss than expected for the weight loss achieved

At the 1mg weekly dose, participants averaged 8.7% weight loss

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