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Particulate formation indicates irreversible aggregation

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A high zeta potential, indicating stronger electrostatic repulsion, can enhance nanoparticle stability by preventing aggregation

Ilic S, Drmic D, Zarkovic K, Kolenc D, Brcic L, Radic B, et al

Two isoforms of B7-H3 are discovered in humans, 2IgB7-H3 ( 3 B7-H3 receptors B7-H3 is known for its dual role in physiology, possessing stimulatory and inhibitory function in cancer development ( 3.1 TLT-2 The first possible receptor identified for 2IgB7-H3 was TLT-2, which was found to bind fusion protein of murine B7-H3 and human IgG1 (B7-H3Ig) in murine T cells

First, the vast majority of available data derives from animal studies, and extrapolation to human applications may not be straightforward due to species differences in physiology and drug metabolism