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Kidney Problems There have been reports of kidney issues, including acute kidney injury, in patients using tirzepatide, particularly those who have experienced severe dehydration from gastrointestinal side effects like vomiting or diarrhea

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Table 2 Effects of the ghrlein on gastrointestinal disorders in animal experiments

This is one reason why many peptide protocols do not necessarily require injections directly into painful or damaged tissues

Certain patients with a personal or family history of specific conditions, like medullary thyroid cancer, may need alternative treatment discussions with their provider