Assessment of the effects of MPTP and paraquat on dopaminergic neurons and microglia in the substantia nigra pars compacta of C57BL/6 mice
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Novel isoforms of NADPH oxidase in vascular physiology and pathophysiology
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3.4.3 Mechanistic insights from preclinical modelsbarrier, immune, and neurotransmitter changes Rodent models of PTSD provide causal evidence that psychological trauma disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance
The dose-response curve has flattened substantially by 4 to 6 mg, while heart-rate and gastrointestinal costs continue to rise above it