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GSH-regulated tumor cell ferroptosis and mechanism study Based on the above research results, NSBSO showed a very strong selective killing ability of tumor cells by exhausting GSH and inhibiting GSH synthesis

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H2O2 is produced in high concentrations by the nicotinamide adenine dinucleotide phosphate (NADPH)-dependent flavoproteins thyroid oxidase DUOX (dual oxidases) 1 and 2 and provides oxidative equivalents for TPO activity [63]

So its important to understand the limitations of the available research

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