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Increasing the dosage and titration is standard, but you dont want to be 12 weeks in, a bit lighter and feeling confident again, about to go from 1 mg per week to 1.7 mg per week, when BOOM

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also showed muscle atrophy was more pronounced after ablation of muscle IGF-1 production than when hepatic IGF-1 production was suppressed (Bikle et al., 2000