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Multi-level anti-inflammatory modulation reduces IL-6, TNF-alpha, and COX-2 expression, dampening the inflammatory response that can delay healing

This inherent stability allows it to remain biologically active for extended periods, a characteristic that makes it suitable for oral administration in research settings, particularly for studies focused on gastrointestinal health

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Journal of Orthopaedic Research, 33 (7), 1024-1033

The biological basis for this is documented in the 2007 Pyo study and the 2018 Pickart review

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