N-Acetyl-L-Cysteine, also known as NAC, is a more stable form of the amino acid L-Cysteine and is the most effective way to boost Glutathione levels in the body
Therefore, any increase in enzyme activity in the blood is important and should be investigated
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However, to get further insight in the role of SLC35A39 in the brain, the generation of specific conditional Slc25a39 knockout mice that carry a deletion of Slc25a39 exclusively in neurons or in the central nervous system may further boost our understanding on the roles and in the importance of SLC25A39 in neuronal tissues
We then used Bodipy-C11 to examine lipid peroxidation, a canonical marker of ferroptosis
We investigated the expression of K16, K17, and Ki67 in mouse skin tissues using immunohistochemical staining