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Importantly, patients using transdermal medications should avoid exposing the patch to external heat sources such as heating pads, electric blankets, hot tubs, saunas, or prolonged direct sunlight, as heat can increase drug absorption and potentially cause overdose

Samples (1 l) were loaded onto a Zorbax 300SB C-18 Nano-HPLC Chip (150 mm75 m, Agilent) with 0.1%(v/v) formic acid (0.6 l/min), and compounds eluted by an increasing 0.1%(v/v) formic acid, acetonitrile gradient (90%(v/v) final)

6 1611-1617 Daniel Leclerc, Sahar Sibani, and Rima Rozen

Dermatologically tested and free from artificial fragrances, parabens, silicones, and other irritants, its ideal for sensitive skin

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and L-carnitine helps shuttle fatty acids toward energy production