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The studys primary outcome was relative liver fat change from baseline at 24 weeks, while secondary outcomes included relative liver fat change from baseline at 48 weeks, absolute liver fat change and percent of participants achieving at least 30% liver fat reduction at weeks 24 and 48

Both approaches are clinically sound

According to the National Drug Dependence Treatment Centre (NDDTC), only 25-35% of patients remain abstinent one year after treatment

While these mechanisms contribute to its therapeutic benefits, they also explain why gastrointestinal side effects are among the most commonly reported adverse reactions

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The jump from placebo to 5mg is massive: 2.4% to 16%