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This study was part of a call to action for more diverse images in textbooks

If youve spent the last year fielding questions about GLP-1 costs from your employer clients, we have news youll want to share and a date to put on the calendar

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The SURMOUNT-5 head-to-head comparison trial provided definitive evidence of tirzepatide's superiority over semaglutide, with Zepbound producing 20.2% average weight loss compared to 13.7% for Wegovy, a 47% greater relative reduction

Systemic effects less commonly include mild dizziness or lightheadedness (may be copper-related), temporary nausea or headache (typically resolves within hours), mild fatigue (rare, reported with higher doses), and transient flu-like symptoms (very rare, may relate to systemic inflammatory response)

The peptideantibody conjugate GIPR-Ab/GLP-1 is a fully human monoclonal anti-human GIPR antagonist antibody (GIPR-Ab) conjugated by amino acid linkers to two GLP-1 analogues