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Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-B signaling pathways

We used the Preacher and Hayes bootstrapping method, as implemented in the mediation (v4.5.0) R package 75 , using general linear models with sex and country of recruitment as covariates

It was confirmed that hydrophobic groups in the Nindol position were indispensable for improving in vitro inhibitory potency against XO

Type 2 diabetes mellitus and skeletal muscle metabolic function

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Here, we demonstrate that deletion of gliT results in transformants which cannot grow in the presence of even modest levels of exogenous gliotoxin and that exogenous gliotoxin up-regulates gene expression within the gliotoxin cluster, especially that of gliT