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Deletion of GIP receptor has been found to counteract high-fat diet induced weight gain in mice, suggesting a causal role of GIP in development of obesity [36]

A multicenter randomized study of 420 patients found that taking CoQ10 in addition to standard therapies helped reduce mortality in patients with severe heart failure

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The estrobolome produces an enzyme (beta-glucuronidase) that breaks down active estrogen which helps the liver detox and filter used estrogen and maintain proper hormone levels throughout the body [1]

Intravenous rather than oral supplementation is recommended because it is likely to ensure higher levels of carnitine in the blood (L-carnitine has poor gastrointestinal bioavailability, which is further compromised by digestive dysfunction)

Avoid excessive cardio, as it can increase muscle loss and elevate cortisol, which may hinder weight loss