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The peptide is constructed on a GIP receptor backbone with non-coded amino acid residues (Aib2, Aib20, aMeL13) and a C20 fatty diacid moiety that enables albumin binding, extending pharmacokinetic half-life for once-weekly administration in research settings

doi: 10.1038/s41374-018-0021-z 176 Di MarzoVBifulcoMDe PetrocellisL

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