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The expression diversity of IGF-I and the IGFBPs in a tissue-specific manner coupled with a large circulating pool adds several levels of complexity to our understanding of the role of the IGF-I/IGFBP system
For anti-obesity drugs to be widely adopted, they must not only demonstrate clinical efficacy but also provide a favorable costbenefit ratio compared to existing treatments
The localized injection strategy aims to maximize effects in specific muscles while minimizing systemic exposure
Costa, M., Canale, D., Filicori, M., D'lddio, S., and Lenzi, A
This gives the drug more stability and longer activity so it can be used in the long term in both diabetes and weight loss
It is also exposure
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