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For ingredient sourcing, buyers should evaluate bulk N-acetyl-L-cysteine powder by identity, assay, related substances, moisture, residual solvents where relevant, heavy metals, microbiology, particle size, odor profile, storage and destination-market requirements

doi:10.1016/j.bjps.2009.05.039 Pisano C, Pratesi G, Laccabue D, Zunino F, Lo Giudice P, Bellucci A, Pacifici L, Camerini B, Vesci L, Castorina M, Cicuzza S, Tredici G, Marmiroli P, Nicolini G, Galbiati S, Calvani M, Carminati P, Cavaletti G (2003) Paclitaxel and cisplatin-induced neurotoxicity: a protective role of acetyl-l-carnitine

however, some discontinuations were actually due to "perceived excessive weight loss," highlighting the potency of the drug

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Further research is needed to understand the effects of GHS on physiology