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Ziani L, Chouaib S, Thiery J
FIGURE 7 The strong role of severe oxidative stress, reduced antioxidant defenses like GSH with increased lipid peroxidation and malondialdehyde generation (213), lipid, protein and DNA oxidation with increased apoptosis and necrosis in atherosclerosis as a major cause of cardiovascular diseases and stroke, supports the use of complementary and alternative medicines, dietary supplements, and antioxidants with hardly any adverse effect, able to restore homeostasis reversing oxidative stress (214)
If it goes the estrogen route, androstenedione is converted (using CYP19A1) first to estrone (E1), which is then converted (using 17-HSD) into estradiol.[ref] Here is a flow chart to give you a better idea of the conversion of cholesterol into estrogen, including the genes that are involved
She combines an engineering mindset with a biological systems approach to explain how genetic differences impact your optimal health.
& Ostrikov, K
Oxidative Stress and Antioxidant Defense Mechanisms in CLDs 2.1
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