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Furthermore, the term Receptor Grade refers to the higher purity of this research reagent when compared to alternatives such as Media Grade IGF-1 LR3

Studies reported that induction of HIF-1 with TLR signalling also enhances the production of inflammatory cytokines (IL-6, IL-8, TNF-), MMPs (MMP- 1, MMP-3, MMP-9), and VEGF, thereby escalating the inflammatory state within the RA synovium 47

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Available from: Johannsen P, Ostergaard K, Christensen JE, Worm M, Rasmussen K