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for example, citrulline serves as a precursor for arginine synthesis and contributes to systemic nitrogen metabolism and nitric oxide signaling [98]

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doi: 10.2337/db08-0958 131 NauckMAHeimesaatMMBehleKHolstJJNauckMSRitzelRet al

After that many other studies have found that H 2 S is synthesized also in other animal tissues and its physiological role has been widely discussed [35]

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