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Back Brown JC, Dryburgh JR, (1971) 'A gastric inhibitory polypeptide II

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Over the course of treatment, the study participants lost weight, their cardiometabolic parameters improved and their free testosterone levels which tend to be elevated in women with PCOS decreased

In contrast, GLP-1 receptor agonists improve metabolic health and may improve endogenous testosterone production without impairing spermatogenesis, Werthman explained

It is a mix of behavior and biology, but I would say it leans heavily toward biology. When you lose weight, the body employs a number of defense mechanisms

Additionally, these medications can affect how the body absorbs other drugs and doctors may need to monitor certain medications more closely