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Looking forward, three key research priorities emerge: (1) Mechanistic Elucidation: Future work must precisely define organelle-specific mechanisms, particularly the potential role of lipid droplet-mitochondria cross-talk in airway epithelial cells, and validate these pathways in human COPD samples

In sleep studies, an increase in deep NREM phases and an improvement in overall sleep quality have been observed

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The comprehensive search method is provided in Supplementary Table S1

However, it can sometimes cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and constipation, especially when starting treatment or increasing the dose