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Behavioural testing was commenced post-weaning at week 5 and conducted weekly, until week 14 for all three cohorts (untreated Pla2g6 / , high-dose semaglutide (0.5 g/g) treated Pla2g6 / and wild-type mice)

Glucagon promotes fat oxidation specifically, which theoretically could shift the weight loss composition toward greater fat loss and less muscle loss compared to pure appetite-suppressing approaches

Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog, Ionescu M, Frohman LA, Journal of Clinical Endocrinology & Metabolism (2006, Vol