Treating cells with cumene hydroperoxide was shown to enhance eryptosis, whereas the antioxidant NAC mitigated this process by enhancing RBC deformability and reducing levels of ROS, calcium, and PS exposure, and demonstrated that oxidative stress plays a crucial role in eryptosis, with pro-oxidants promoting and antioxidants limiting eryptotic processes [413]
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The 3D structure of ES7L is highlighted as a red ribbon in Fig 3A
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