GSH offers protection against unstable molecules known as free radicals that cause damage to cells, DNA, and proteins, leading to various diseases and aging
However, -EC does not accumulate intracellularly in most species, because GCL catalyzing -EC synthesis is a rate-limiting enzyme and synthesized -EC is immediately converted to GSH by GS (Fig
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NAFLD has become increasingly common in the UK, affecting approximately one in three adults, often associated with obesity, type 2 diabetes, and metabolic syndrome
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