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NCTC1469 cells, a normal mouse hepatocyte cell line, were obtained from the American Type Culture Collection and were cultured in DMEM containing 10% (v/v) fetal horse serum, 2 mM glutamine, 5 U/mL penicillin, and 50 g/mL streptomycin at 37 C in a humidified O 2 /CO 2 (19:1) atmosphere

Therefore, GSH depletion-induced oxidative stress and cell death depend on the combination of inducer and cell-specific molecular characteristics, i.e

Zhang, H., Feng, Y

cerevisiae and phosphoglycerate kinase promoter (PGK1) of S

ACOX1, acyl-coA oxidase 1

Described herein are otic formulations or compositions with an ionic balance that is compatible with the perilymph and/or the endolymph and does not cause any change in cochlear potential