2024;103(26):e38668
69 Wound healing has been an active area of research, and the use of GLP-1RAs has been shown to improve wound healing by increasing keratinocyte migration, PI3K/Akt activation, increasing fibroblasts, myofibroblasts, and vessel density, activation of AMPK, and decreasing CRP and MMP-9/TIMP-1 ratio
Diabetic ketoacidosis (DKA) While considered lower-risk than with SGLT2 inhibitors, DKA can still occur in people with type 1 diabetes taking tirzepatide, particularly if the insulin dose is reduced too aggressively or if the person becomes unwell (e.g
37: 23543 Bohmer T, Rydning A, Solberg HE
J., Strasser, A
Open access funding provided by Royal Library, Copenhagen University Library Ethics declarations Competing interests PR received grants from AstraZeneca, Bayer, Novo Nordisk A/S, as well as consulting fees from AstraZeneca, Astellas, Bayer, Boehringer Ingelheim, Gilead, Merck, Mundipharma, Novo Nordisk A/S and Sanofi