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In addition, diabetes is an independent risk factor for cardiovascular disease and, alongside smoking, obesity, dyslipidaemia and hypertension, is one of the most important risk factors for heart disease and stroke worldwide [3, 4]

Patients should avoid carbonated beverages, which can increase bloating and discomfort, and instead choose water or unsweetened drinks

Comparative effectiveness: Head-to-head trials vs tirzepatide to quantify the incremental benefit Track the trials: Visit ClinicalTrials.gov to see all ongoing retatrutide studies, eligibility criteria for enrollment, and recruiting sites

GI motility (ghrelin-mimetic peripheral effect) Ghrelin receptors are expressed in the gastrointestinal tract where ghrelin promotes gastric motility

Always follow the storage instructions supplied with the investigational product