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Semaglutide is a breakthrough medication belonging to a class of drugs known as GLP-1 (Glucagon-Like Peptide-1) receptor agonists

The SELECT trial demonstrated a 38% CRP reduction regardless of baseline BMI, statin use, or cholesterol levels

It is a 31 amino acid long peptide hormone (7) mainly secreted by enteroendocrine L cells in the distal intestine, alpha cells in the pancreas, and by the preproglucagon (PPG) neurons located in the nucleus of the solitary tract of the caudal brainstem (6)

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When to Seek Immediate Medical Attention Contact your healthcare provider or seek emergency care if you experience: Severe abdominal pain that does not go away Signs of an allergic reaction (rash, swelling, difficulty breathing) Symptoms of pancreatitis (severe abdominal pain, vomiting) Symptoms of severe dehydration (dizziness, confusion, rapid heartbeat) FDA Adverse Event Reporting To report medication side effects to the FDA, visit www.fda.gov/medwatch or call 1-800-FDA-1088

Across age groups, awareness of these drugs is highest among older adults