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More rarely, patients can experience joint swelling, joint pain, carpal tunnel syndrome, and an increased risk of diabetes

UV exposure triggers cascading damage through reactive oxygen species (ROS) generation, MMP activation, and inflammatory signalling, ultimately leading to collagen fragmentation and elastin disorganisation

Meyer A, Laverny G, Allenbach Y, Grelet E, Ueberschlag V, Echaniz-Laguna A, et al

Loss of pericytes may result in microvascular instability, causing diminished capillary perfusion in diabetic retinopathy [84]

Xue et al., 2023), further supporting the role of this class of molecules in modulating cancer cell behavior