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Tirzepatide demonstrated superior weight loss (up to 22% in clinical trials) compared to semaglutide alone

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Additionally, we used Pdx1-Cre;Trp53 R172H ;Rb f/f mice, which developed endogenous insulinoma and glucagonoma, since they enabled differential imaging evaluation of our probe in functional pancreatic neuroendocrine neoplasms

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More recently, however, an animal study based on a tandem stenosis mouse model showed the ability of SGLT2is to stabilize atherosclerotic plaques, with increased fibrosis, augmented collagen accumulation, and significant upregulation of the expression of vasculoprotective NADPH oxidase 4 [18]

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