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CAFs are a large and heterogeneous cell population within the intricate TME, playing complex roles in regulating tumour growth

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These systems are responsible for clearing out waste, toxins, and used hormones

This increases the risk of a heart attack, when blood flow to the heart muscle is compromised

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Limitations of Patch Testing While patch testing can provide valuable diagnostic insight, there are several scenarios where it may offer little benefit or even delay systemic or targeted treatment strategies (Table 2)