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Multivariate analysis showed no difference between placebo and liraglutide arms in HbA1c at 6 months (HbA1c:0.2 mmol/mol, 11.3, 11.6, p = 0.98) however, at 12 months HbA1c was significantly higher in the liraglutide arm (HbA1c:10.9 mmol/mol, 1.1, 20.6, p = 0.032)

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While you don't need to be as surgically precise about fasting around the moment of administration, maintaining stable blood sugar and avoiding large insulin spikes will still allow the peptide to work more effectively in the background

Example: If a patient started therapy at BMI 37 and now has BMI 31 after successful treatment, the provider may attest to the BMI at initiation if documented appropriately

Metabolism Support: It supports the metabolism of fats and proteins, which indirectly supports attempts at weight loss

The visible "Ozempic face" pattern, the demand for treatment, and the response to combination interventions