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What does the research say about how far off we are versus where we need to be, how close to failure you need to train to build muscle, and then how to actually fix how hard you train, as well as a little trick I have toward the end of the episode

The management of these side effects is multifaceted

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The mechanism involves suppression of reactive oxygen species (ROS) that the enteric nervous system uses to trigger peristaltic contractions, combined with microbiome shifts away from butyrate-producing bacteria