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Fatigue is a recognised side effect of Wegovy (semaglutide 2.4 mg), a GLP-1 receptor agonist licensed in the UK for weight management

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In conclusion, the GLP-1 analogue semaglutide decreased alcohol intake across different drinking models and species and modulated central GABA neurotransmission, providing support for clinical testing of semaglutide as a potentially novel pharmacotherapy for AUD